RAF Typhoon FGR4s have operated alongside France's air force in a joint strike targeting an underground arms cache in Syria employed by the Daesh militant organization, according to the UK's MoD.
The site, identified by surveillance, was believed to be housing weapons and explosive materials, the release indicated, and was located in hills just above the ancient city of Palmyra in the heart of Syria.
"The RAF jets used Paveway IV guided bombs to hit a number of access tunnels leading to the depot... early reports suggest the strike was effective," the ministry announced.
There was no sign of any civilian casualties in the strike on Saturday evening and all the aircraft returned to base without incident, the ministry further stated.
The British jets were backed up by a Voyager tanker plane.
IS - also known as the so-called Islamic State - imposed extremist governance over parts of Iraq and Syria prior to its 2019 collapse.
"This strike underscores our UK leadership, and commitment to operate in unison with our allies, to eliminate any resurgence of the terrorist group and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief John Healey stated.
British military aircraft have conducted surveillance missions over Syria to "forestall any attempted comeback" of IS following its military defeat at the Baghuz confrontation in 2019, the MoD reported.
"I must thank all the members of British forces participating in this strike for their professionalism and their courage," Healey commented. "They were part of a great many British troops deployed over Christmas and New Year. This operation, to eliminate militants who endanger our safety, shows how our armed forces are always on standby, all year round, ensuring Britain's security within its borders and influential overseas."
Last December, the American forces carried out what it called a "massive strike" on Daesh sites in the country, subsequent to an assault resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The U.N. estimates Daesh still has roughly 5-7 thousand fighters in both countries.